Experimental Biology and Medicine | Genomics, Proteomics and Bioinformatics

Original Research

Published on 30 Jan 2026

Causal effects of antibody-mediated immunity to pathogens on five ophthalmic diseases: a Mendelian randomization study

in Genomics, Proteomics and Bioinformatics

Liduo Pan
Jian Deng
Jianli Yang
Meng Wang
Zheng Chen
Tao Wang
Yonghao Li

Experimental Biology and Medicine

doi 10.3389/ebm.2026.10906

Original Research

Published on 22 Jan 2026

Altered MCF2L-AS1 expression and correlation with the prognosis of diabetic nephropathy

in Genomics, Proteomics and Bioinformatics

Nastaran Injinari
Morteza Hadizadeh
Nasim Namiranian
Seyed Mehdi Kalantar
Ali Dehghani Firoozabadi
Samira Asadollahi

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10771

157 views

Original Research

Published on 14 Jan 2026

Machine learning-based comprehensive analysis of m6A RNA methylation regulators in colorectal cancer: implications for prognosis, immune microenvironment, and immunotherapy response

in Genomics, Proteomics and Bioinformatics

Feifei Kong
Jiawei Feng
Haixia Shan
Youlong Zhu
Ling-Jun Zhu

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10776

362 views

Original Research

Published on 12 Jan 2026

Tear proteomic analysis in keratoconus patients and potential biomarkers: a case-control study

in Genomics, Proteomics and Bioinformatics

Daniel de Almeida Borges
Marcos Rodrigo Alborghetti
Romenia Ramos Domingues
Adriana Franco Paes Leme
Mônica Alves

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10864

181 views

Original Research

Published on 15 Oct 2025

TIMAP downregulation in Burkitt’s lymphoma reveals key molecules and signaling pathways in B-cell lymphomagenesis

in Genomics, Proteomics and Bioinformatics

Marya Obeidat
Saleh Tadros
Batool Ismail
Ayah Al-Khaldi

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10533

4,421 views

Original Research

Published on 15 Oct 2025

Glaucoma and cardiovascular disease: a bidirectional two-sample Mendelian randomization analysis

in Genomics, Proteomics and Bioinformatics

Dongdong Jin
Jie Sun
Wei Zhang
Mingxuan Zhang
Chengfang Li

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10610

4,970 views

Original Research

Published on 01 Oct 2025

Unveiling the dual role of CD3G: a diagnostic biomarker for depression and its oncogenic implications

in Genomics, Proteomics and Bioinformatics

Hai Gao
Ting Wu
Jihui Xue
Jing Liu
Dongmei Wen
Guanwei Huang

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10599

4,370 views
1 citation

Original Research

Published on 25 Sep 2025

Multi-omics analysis identifies the unique high-FDCSP basal cells in triple-negative breast cancer

in Genomics, Proteomics and Bioinformatics

Xinya Lu
Zhen Chen
Ying Shao

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10632

4,993 views

Original Research

Published on 19 Sep 2025

Prognostic significance and therapeutic implications of redox metabolism-related genes in head and neck squamous cell carcinoma

in Genomics, Proteomics and Bioinformatics

Lina Yang
Jingyu Hai
Jiayi Liu
Shaohua Shen
Lin Su
Juan Sun

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10623

2,190 views

Original Research

Published on 29 Aug 2025

Integrated analysis of metabolome and microbiome in a mouse model of sodium valproate-induced autism

in Genomics, Proteomics and Bioinformatics

Shuzhen Zhao
Xinyan Zhang
Yanqiu Miao
Xueya Gao
Qiuhua Wan
Wei Qiu
Haixia Si
Yingjie Han
Xiao Du
Yuanyuan Feng

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10452

5,905 views

Original Research

Published on 29 Aug 2025

RNA binding proteins potentially regulate alternative splicing of immune-related genes during the progression of coronary artery disease

in Genomics, Proteomics and Bioinformatics

Yulin Miao
Lei Wang
Gang Zhao
Wei Gou
Shan Chen
Chao Ding
Zongxin Li
Fengli Gao

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10430

5,540 views

Original Research

Published on 04 Aug 2025

Dietary-related characteristics and cataract risk: evidence from a mendelian randomization study

in Genomics, Proteomics and Bioinformatics

Chen Li
Yicheng Lu
Mingxuan Chen
Qing Zhang
Zhe Zhang
Wenqun Xi
Weihua Yang

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10544

6,406 views
1 citation

Original Research

Published on 17 Jul 2025

Comprehensive identification of pathogenic tandem repeat expansions in sporadic amyotrophic lateral sclerosis: advantages of long-read vs. short-read sequencing

in Genomics, Proteomics and Bioinformatics

Eleonora Sabetta
Karin Rallmann
Jonas Bergquist
Pille Taba
Abigail L. Pfaff
Bal Hari Poudel
Davide Ferrari
Massimo Locatelli
Sulev Kõks

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10593

1,882 views

Original Research

Published on 11 Jul 2025

An innovative full-size pathogenic tandem duplication mutation precise detection system based on next-generation sequencing

in Genomics, Proteomics and Bioinformatics

Li-Li Zhang
Zhe Wang
Ying Zhou
Dai-Yang Li
Xiao-Nian Tu
Yu-Xia Li
Ke-Ming Du
Zhong-Zheng Zheng

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10128

1,071 views

Original Research

Published on 03 Jun 2025

Retrotransposition-competent L1s are increased in the genomes of individuals with amyotrophic lateral sclerosis

in Genomics, Proteomics and Bioinformatics

Abigail L. Pfaff
Sulev Kõks

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10575

1,447 views
2 citations

Original Research

Published on 29 May 2025

The landscape of non-reference SINE-VNTR-Alus in amyotrophic lateral sclerosis

in Genomics, Proteomics and Bioinformatics

Abigail L. Pfaff
Vivien J. Bubb
John P. Quinn
Sulev Kõks

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10600

1,531 views

Original Research

Published on 30 Apr 2025

Aberrant DNMT1-mediated DACH1 methylation is associated with colorectal adenoma-to-carcinoma progression

in Genomics, Proteomics and Bioinformatics

Yan Zhang
Honggang Liu

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10469

1,377 views
1 citation

Original Research

Published on 15 Jan 2025

Function of formyl peptide receptor 2 in adriamycin resistance of breast cancer

in Genomics, Proteomics and Bioinformatics

Landi Su
Jingjing Li
Li Qin
Yang Feng
Dingwen Xu

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10281

1,384 views

Original Research

Published on 08 Jan 2025

Whole blood transcriptome profile identifies motor neurone disease RNA biomarker signatures

in Genomics, Proteomics and Bioinformatics

Sulev Kõks
Karin Rallmann
Mari Muldmaa
Jack Price
Abigail L. Pfaff
Pille Taba

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10401

1,741 views
2 citations

Original Research

Published on 23 Sep 2024

Integrated multi-omics profiling reveals the ZZZ3/CD70 axis is a super-enhancer-driven regulator of diffuse large B-cell lymphoma cell-natural killer cell interactions

in Genomics, Proteomics and Bioinformatics

Xi Li
Juya Cui
Liao Wang
Caihong Cao
Hu Liu

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10155

3,225 views

Correction

Published on 19 Sep 2024

Corrigendum: Genome-wide association study identifying variants related to performance and injury in high-performance athletes

in Genomics, Proteomics and Bioinformatics

Jay R. Ebert
Agnes Magi
Eve Unt
Ele Prans
David J. Wood
Sulev Koks

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10348

1,015 views

Review

Published on 18 Sep 2024

Single-cell RNA sequencing data locate ALDH1A2-mediated retinoic acid synthetic pathway to glomerular parietal epithelial cells

in Genomics, Proteomics and Bioinformatics

Wen-Bin Liu
Damian Fermin
An-Long Xu
Jeffrey B. Kopp
Qihe Xu

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10167

4,724 views

Original Research

Published on 22 Jul 2024

The causal relationship between autoimmune diseases and rhinosinusitis, and the mediating role of inflammatory proteins: a Mendelian randomization study

in Genomics, Proteomics and Bioinformatics

Yanjing Liang
Shao Yin
Xiangyan Chen
Chengen Li
Qiu Chen

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10196

2,801 views
7 citations

Original Research

Published on 09 Jul 2024

Identification of potential biomarkers for cerebral palsy and the development of prediction models

in Genomics, Proteomics and Bioinformatics

Haoyang Zheng
Duo Zhang
Yong Gan
Zesheng Peng
Yuyi Wu
Wei Xiang

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10101

2,149 views
4 citations

28 articles

articles

Causal effects of antibody-mediated immunity to pathogens on five ophthalmic diseases: a Mendelian randomization study

Altered MCF2L-AS1 expression and correlation with the prognosis of diabetic nephropathy

Machine learning-based comprehensive analysis of m6A RNA methylation regulators in colorectal cancer: implications for prognosis, immune microenvironment, and immunotherapy response

Tear proteomic analysis in keratoconus patients and potential biomarkers: a case-control study

TIMAP downregulation in Burkitt’s lymphoma reveals key molecules and signaling pathways in B-cell lymphomagenesis

Glaucoma and cardiovascular disease: a bidirectional two-sample Mendelian randomization analysis

Unveiling the dual role of CD3G: a diagnostic biomarker for depression and its oncogenic implications

Multi-omics analysis identifies the unique high-FDCSP basal cells in triple-negative breast cancer

Prognostic significance and therapeutic implications of redox metabolism-related genes in head and neck squamous cell carcinoma

Integrated analysis of metabolome and microbiome in a mouse model of sodium valproate-induced autism

RNA binding proteins potentially regulate alternative splicing of immune-related genes during the progression of coronary artery disease

Dietary-related characteristics and cataract risk: evidence from a mendelian randomization study

Comprehensive identification of pathogenic tandem repeat expansions in sporadic amyotrophic lateral sclerosis: advantages of long-read vs. short-read sequencing

An innovative full-size pathogenic tandem duplication mutation precise detection system based on next-generation sequencing

Retrotransposition-competent L1s are increased in the genomes of individuals with amyotrophic lateral sclerosis

The landscape of non-reference SINE-VNTR-Alus in amyotrophic lateral sclerosis

Aberrant DNMT1-mediated DACH1 methylation is associated with colorectal adenoma-to-carcinoma progression

Function of formyl peptide receptor 2 in adriamycin resistance of breast cancer

Whole blood transcriptome profile identifies motor neurone disease RNA biomarker signatures

Integrated multi-omics profiling reveals the ZZZ3/CD70 axis is a super-enhancer-driven regulator of diffuse large B-cell lymphoma cell-natural killer cell interactions

Corrigendum: Genome-wide association study identifying variants related to performance and injury in high-performance athletes

Single-cell RNA sequencing data locate ALDH1A2-mediated retinoic acid synthetic pathway to glomerular parietal epithelial cells

The causal relationship between autoimmune diseases and rhinosinusitis, and the mediating role of inflammatory proteins: a Mendelian randomization study

Identification of potential biomarkers for cerebral palsy and the development of prediction models