Experimental Biology and Medicine

Original Research

Published on 12 Jun 2026

Phenotypic profiling of Pathogen Box compounds MMV667494 and MMV028694 in bloodstream-form Trypanosoma brucei brucei

in Infectious Diseases

Pearl Ihuoma Akazue
Neils Ben Quashie
Sue Vaughan
Harry P. de Koning
Theresa Manful Gwira

Experimental Biology and Medicine

doi 10.3389/ebm.2026.10979

Brief Communication

Published on 03 Dec 2025

ApoE COG 133 mimetic peptide improves survival, infection burden, and Clostridioides difficile toxin-A-induced intestinal damage in mice

in Infectious Diseases

Orleâncio G. R. de Azevedo
Jae H. Shin
Rosemayre S. Freire
Gabriella C. V. Ciurleo
Gerly A. C. Brito
Michael P. Vitek
Richard L. Guerrant
Reinaldo B. Oriá
Cirle A. Warren

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10638

886 views

Original Research

Published on 03 Oct 2025

Deciphering the microbiological mechanism of Tongxie Yaofang in treating IBS-D: a multimodal mechanistic study in mice integrating network pharmacology, computational simulation, and 16S rRNA sequencing

in Infectious Diseases

Donglin Yu
Qianghong Tian
Junxi Shen
Leyao Fang
Zhoujin Tan
Ying Cai

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10725

6,847 views

Original Research

Published on 13 Aug 2025

Gestational exposure to HIV drugs alters intestinal mucosa-associated microbial diversity in adult rat offspring

in Infectious Diseases

Yaswanthi Yanamadala
Chandra Mohan Reddy Muthumula
Kuppan Gokulan
Kumari Karn
Vicki Sutherland
Helen Cunny
Janine H. Santos
Sangeeta Khare

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10564

7,375 views
1 citation

Review

Published on 24 Jul 2025

Insights into the expansion of Oropouche virus in Brazil: epidemiological and environmental aspects

in Infectious Diseases

Igor Pereira Godinho
Ítalo Faria Dória
Victor de Melo Rocha
Bárbara Alves Miranda
Lucas Fernandes Chamhum Salomão
Brunello Stancioli
Adriana Alves Oliveira Paim
Jordana G. Alves Coelho dos Reis
Samille Henriques Pereira
Flávio Guimarães da Fonseca

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10647

2,369 views
2 citations

Original Research

Published on 21 Jul 2025

Functional antibody responses to SARS-CoV-2 variants before and after booster vaccination among adults in Ghana

in Infectious Diseases

F. D. Partey
A. N. A. Pobee
I. K. Damptey
F. Osei
M. M. A. K. Owusu-Amponsah
Y. A. A. Ansah
C. Ye
S. Bradfute
I. Hurwitz
P. K. Quashie

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10440

1,373 views
1 citation

Original Research

Published on 06 Jun 2025

Biofilm and surface-motility profiles under polymyxin B stress in multidrug-resistant KAPE pathogens isolated from Ghanaian hospital ICUs

in Infectious Diseases

Molly K. Abban
Eunice Ampadubea Ayerakwa
Abiola Isawumi

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10350

1,665 views
2 citations

Original Research

Published on 21 May 2025

Effect of in utero and lactational exposure to antiretroviral therapy on the gut microbial composition and metabolic function in aged rat offspring

in Infectious Diseases

Chandra Mohan Reddy Muthumula
Yaswanthi Yanamadala
Kuppan Gokulan
Kumari Karn
Helen Cunny
Vicki Sutherland
Janine H. Santos
Sangeeta Khare

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10468

2,125 views
3 citations

Original Research

Published on 06 May 2025

Vaccination with synthetic long peptide and CpG 2395 in AddaVax induces potent anti-tumor effects

in Infectious Diseases

Shanshan Jiang
Shuqi Zhao
Qiaojiajie Zhao
Yinfang Wang
Weihua Zhang
Yangmeng Feng
Lijie Zhang

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10509

1,780 views

Review

Published on 11 Feb 2025

Bone marrow immune cells and drug resistance in acute myeloid leukemia

in Infectious Diseases

Miao Zhang
You Yang
Jing Liu
Ling Guo
Qulian Guo
Wenjun Liu

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10235

3,706 views
8 citations

Brief Communication

Published on 29 Jan 2025

Functional mass spectrometry indicates anti-protease and complement activity increase with COVID-19 severity

in Infectious Diseases

Douglas D. Fraser
Swapan Roy
Matt Kuruc
Maritza Quintero
Logan R. Van Nynatten
Gediminas Cepinskas
Haiyan Zheng
Amenah Soherwardy
Devjit Roy

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10308

1,837 views
2 citations

Original Research

Published on 03 Jan 2025

scRNA-seq reveals elevated interferon responses and TNF-α signaling via NFkB in monocytes in children with uncomplicated malaria

in Infectious Diseases

Collins M. Morang’a
Riley S. Drake
Vincent N. Miao
Nancy K. Nyakoe
Dominic S. Y. Amuzu
Vincent Appiah
Yaw Aniweh
Yaw Bediako
Saikou Y. Bah
Alex K. Shalek

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10233

2,947 views
3 citations

Original Research

Published on 20 Nov 2024

Predicting severe COVID-19 using readily available admission indicators: SpO2/FiO2 ratio, comorbidity index, and gender

in Infectious Diseases

Luan D. Vu
Rebecca C. Christofferson
Hollis R. O’Neal
Diana Hamer
Anh T. Q. Phan
Katie M. Vance
E. A. Turner
Avinash Kumar
Ibrahim Musa Yola
Natalie Lim

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10193

1,648 views

Original Research

Published on 14 Oct 2024

Immunization with recombinant Streptococcus pneumoniae PgdA protects mice against lung invasion

in Infectious Diseases

Jiangming Xiao
Bichen Liu
Yibing Yin
Xuemei Zhang

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10119

1,616 views
1 citation

Original Research

Published on 21 Jun 2024

Attenuated mutants of Salmonella enterica Typhimurium mediate melanoma regression via an immune response

in Infectious Diseases

Genesy Pérez Jorge
Marco Gontijo
Marina Flóro e Silva
Isabella Carolina Rodrigues Dos Santos Goes
Yessica Paola Jaimes-Florez
Lilian de Oliveira Coser
Francisca Janaína Soares Rocha
Selma Giorgio
Marcelo Brocchi

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10081

2,036 views
7 citations

Original Research

Published on 02 Apr 2024

Clinical outcomes and immunological response to SARS-CoV-2 infection among people living with HIV

in Infectious Diseases

Esimebia Adjovi Amegashie
Prince Asamoah
Lawrencia Emefa Ami Ativi
Mildred Adusei-Poku
Evelyn Yayra Bonney
Emmanuel Ayitey Tagoe
Elijah Paintsil
Kwasi Torpey
Osbourne Quaye

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10059

2,700 views
8 citations

Original Research

Published on 15 Feb 2024

Exploring the transmission modalities of Bunyamwera virus

in Infectious Diseases

Erik A. Turner
Rebecca C. Christofferson

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10114

1,732 views
4 citations

17 articles

articles

Phenotypic profiling of Pathogen Box compounds MMV667494 and MMV028694 in bloodstream-form Trypanosoma brucei brucei

ApoE COG 133 mimetic peptide improves survival, infection burden, and Clostridioides difficile toxin-A-induced intestinal damage in mice

Deciphering the microbiological mechanism of Tongxie Yaofang in treating IBS-D: a multimodal mechanistic study in mice integrating network pharmacology, computational simulation, and 16S rRNA sequencing

Gestational exposure to HIV drugs alters intestinal mucosa-associated microbial diversity in adult rat offspring

Insights into the expansion of Oropouche virus in Brazil: epidemiological and environmental aspects

Functional antibody responses to SARS-CoV-2 variants before and after booster vaccination among adults in Ghana

Biofilm and surface-motility profiles under polymyxin B stress in multidrug-resistant KAPE pathogens isolated from Ghanaian hospital ICUs

Effect of in utero and lactational exposure to antiretroviral therapy on the gut microbial composition and metabolic function in aged rat offspring

Vaccination with synthetic long peptide and CpG 2395 in AddaVax induces potent anti-tumor effects

Bone marrow immune cells and drug resistance in acute myeloid leukemia

Functional mass spectrometry indicates anti-protease and complement activity increase with COVID-19 severity

scRNA-seq reveals elevated interferon responses and TNF-α signaling via NFkB in monocytes in children with uncomplicated malaria

Predicting severe COVID-19 using readily available admission indicators: SpO2/FiO2 ratio, comorbidity index, and gender

Immunization with recombinant Streptococcus pneumoniae PgdA protects mice against lung invasion

Attenuated mutants of Salmonella enterica Typhimurium mediate melanoma regression via an immune response

Clinical outcomes and immunological response to SARS-CoV-2 infection among people living with HIV

Exploring the transmission modalities of Bunyamwera virus