Experimental Biology and Medicine | Physiology, Pathophysiology and Mechanisms of Disease

Review

Published on 01 May 2026

Ferroptosis and futile recanalization after mechanical thrombectomy in acute ischemic stroke: mechanisms, risk factors, predictive models and therapeutic interventions

in Physiology, Pathophysiology and Mechanisms of Disease

Yuexin Wu
Cuiying Zhang
Yangyang Peng
Longlong Liu

Experimental Biology and Medicine

doi 10.3389/ebm.2026.10997

Original Research

Published on 30 Mar 2026

Lymphatic pumping technique in mice alters blood parameters and metastatic melanoma in an age-dependent manner

in Physiology, Pathophysiology and Mechanisms of Disease

Christopher Walsh
Matthew Kirstein
Elise Wagner
Emily Scott
Jerome Walsh
Shashank Reddy
Nathan Hoggard
Arshad Ahmad
Reetobrata Basu
Sam Mathes

Experimental Biology and Medicine

doi 10.3389/ebm.2026.10850

332 views

Original Research

Published on 20 Mar 2026

Towards a standardized diabetic prolonged wound healing model in hairless SKH1 mice

in Physiology, Pathophysiology and Mechanisms of Disease

Elle Koivunotko
Julia Monola
Chris S. Pridgeon
Jere Linden
Riina Harjumäki
Emrah Yatkin
Mari Madetoja
Marjo Yliperttula

Experimental Biology and Medicine

doi 10.3389/ebm.2026.10857

275 views

Original Research

Published on 24 Feb 2026

L-Glutamine attenuates peritoneal fibrosis developed in 5-Fluorouracil-treated mice

in Physiology, Pathophysiology and Mechanisms of Disease

Juliana Francisca Grossi Heleno
Leticia Cristine Cardoso dos Santos
Igor Campos Fontes
Mirielly Ranny Almeida Paiva Silva
Lucas Barbosa Correia
Nayma Drielly Granato Silva
Pedro Henrique Dias Moura Prazeres
Pedro Pires Goulart Guimarães
Derek W. Gilroy
Silvia Passos Andrade

Experimental Biology and Medicine

doi 10.3389/ebm.2026.10755

219 views
1 citation

Original Research

Published on 24 Feb 2026

Intra- and extrapulmonary lipopolysaccharides-induced acute lung injury and pharmacotherapeutic response patterns in ventilated 7-day-old rabbits

in Physiology, Pathophysiology and Mechanisms of Disease

Guiyin Zhuang
Qiang Gu
Siyu Xie
Xiaojing Guo
Bo Sun

Experimental Biology and Medicine

doi 10.3389/ebm.2026.10788

216 views
1 citation

Mini Review

Published on 23 Feb 2026

The gut-retina axis in age-related macular degeneration: immune crosstalk and metabolite production

in Physiology, Pathophysiology and Mechanisms of Disease

Beryl Zhou
Zaid Parekh
Christopher Phung
Sarah H. Rodriguez
Dimitra Skondra

Experimental Biology and Medicine

doi 10.3389/ebm.2026.10847

227 views

Original Research

Published on 30 Jan 2026

Maternal diet-induced hypercholanemia alters gut microbiota and metabolome in adult female Western diet-fed offspring

in Physiology, Pathophysiology and Mechanisms of Disease

Caroline Ovadia
Saraid McIlvride
Josca M. Schoonejans
Konstantina Spagou
Maria Gómez-Romero
Ann Smith
Georgia Papacleovoulou
Vanya Nikolova
Peter H. Dixon
Elaine Holmes

Experimental Biology and Medicine

doi 10.3389/ebm.2026.10810

496 views

Original Research

Published on 22 Sep 2025

Variational autoencoder enhanced analysis of energy metabolism and autophagy in exercising cardiomyocytes

in Physiology, Pathophysiology and Mechanisms of Disease

Liquan Chen
Yun Yang

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10489

1,172 views

Original Research

Published on 28 Aug 2025

An approach to evaluate the effect of inflammatory microvesicles on Ca2+ handling in human-induced pluripotent stem cell-derived cardiomyocytes

in Physiology, Pathophysiology and Mechanisms of Disease

Dania Fischer
Mishkaat Sha’sha’a
Judith Schenz
Aycan Tayan
Christina Mertens
Sebastian O. Decker
Nadia Gallenstein
Maximilian Dietrich
Trim Lajqi
Anna Hafner

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10461

1,274 views

Brief Communication

Published on 14 Aug 2025

Natural killer cell subpopulations in the peripheral blood of single ventricle/hypoplastic left heart syndrome patients via single-cell RNA sequencing

in Physiology, Pathophysiology and Mechanisms of Disease

Hui-Qi Qu
Kushagra Goel
Kayleigh Ostberg
Diana J. Slater
Fengxiang Wang
James Snyder
Cuiping Hou
Garnet Eister
John J. Connolly
Michael March

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10524

3,492 views

Brief Communication

Published on 23 May 2025

N-acetyl-L-cysteine improves mitochondrial and oxidative defects in the acadian variant of fanconi syndrome

in Physiology, Pathophysiology and Mechanisms of Disease

Inas Al-Younis
Rebeca Martín-Jiménez
Mehtab Khan
Yann Baussan
Caroline Jose
Yves Thibeault
Etienne Hebert-Chatelain

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10448

1,508 views

Mini Review

Published on 28 Apr 2025

Primary cilia and inflammatory response: unveiling new mechanisms in osteoarthritis progression

in Physiology, Pathophysiology and Mechanisms of Disease

Yuyan Sun
Ziyu Luo
Yuanyuan Fu
ThaiNamanh Ngo
Wen Wang
Yuanrong Wang
Ying Kong

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10490

4,122 views
7 citations

Retraction

Published on 10 Apr 2025

Retraction: Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats

in Physiology, Pathophysiology and Mechanisms of Disease

EBM Editorial Office

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10605

846 views

Original Research

Published on 11 Feb 2025

A study on the differences in the gut microbiota and metabolism between male and female mice in different stress periods

in Physiology, Pathophysiology and Mechanisms of Disease

Yajun Qiao
Juan Guo
Qi Xiao
Jianv Wang
Xingfang Zhang
Xinxin Liang
Lixin Wei
Hongtao Bi
Tingting Gao

Experimental Biology and Medicine

doi 10.3389/ebm.2025.10204

2,652 views
5 citations

Review

Published on 22 Jul 2024

Legumain in cardiovascular diseases

in Physiology, Pathophysiology and Mechanisms of Disease

Lei Zhou
Jianqiang Wu
Zairong Wei
Yuehong Zheng

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10121

2,737 views
5 citations

Original Research

Published on 19 Apr 2024

Vaporization of perfluorocarbon attenuates sea-water-drowning-induced acute lung injury by deactivating the NLRP3 inflammasomes in canines

in Physiology, Pathophysiology and Mechanisms of Disease

Cheng-Cheng Su
Zhao-Rui Zhang
Jin-Xia Liu
Ji-Guang Meng
Xiu-Qing Ma
Zhen-Fei Mo
Jia-Bo Ren
Zhi-Xin Liang
Zhen Yang
Chun-Sun Li

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10104

2,005 views

Original Research

Published on 05 Apr 2024

Calcium-sensing receptor-mediated macrophage polarization improves myocardial remodeling in spontaneously hypertensive rats

in Physiology, Pathophysiology and Mechanisms of Disease

Jiaqi Zhao
Ning Lu
Yuanyuan Qu
Wei Liu
Hua Zhong
Na Tang
Jiayi Li
Lamei Wang
Dongmei Xi
Fang He

Experimental Biology and Medicine

doi 10.3389/ebm.2024.10112

2,244 views
12 citations

17 articles

articles

Ferroptosis and futile recanalization after mechanical thrombectomy in acute ischemic stroke: mechanisms, risk factors, predictive models and therapeutic interventions

Lymphatic pumping technique in mice alters blood parameters and metastatic melanoma in an age-dependent manner

Towards a standardized diabetic prolonged wound healing model in hairless SKH1 mice

L-Glutamine attenuates peritoneal fibrosis developed in 5-Fluorouracil-treated mice

Intra- and extrapulmonary lipopolysaccharides-induced acute lung injury and pharmacotherapeutic response patterns in ventilated 7-day-old rabbits

The gut-retina axis in age-related macular degeneration: immune crosstalk and metabolite production

Maternal diet-induced hypercholanemia alters gut microbiota and metabolome in adult female Western diet-fed offspring

Variational autoencoder enhanced analysis of energy metabolism and autophagy in exercising cardiomyocytes

An approach to evaluate the effect of inflammatory microvesicles on Ca2+ handling in human-induced pluripotent stem cell-derived cardiomyocytes

Natural killer cell subpopulations in the peripheral blood of single ventricle/hypoplastic left heart syndrome patients via single-cell RNA sequencing

N-acetyl-L-cysteine improves mitochondrial and oxidative defects in the acadian variant of fanconi syndrome

Primary cilia and inflammatory response: unveiling new mechanisms in osteoarthritis progression

Retraction: Hydrogen-rich saline protects myocardium against ischemia/reperfusion injury in rats

A study on the differences in the gut microbiota and metabolism between male and female mice in different stress periods

Legumain in cardiovascular diseases

Vaporization of perfluorocarbon attenuates sea-water-drowning-induced acute lung injury by deactivating the NLRP3 inflammasomes in canines

Calcium-sensing receptor-mediated macrophage polarization improves myocardial remodeling in spontaneously hypertensive rats